Publications

Peer-reviewed journal publications and pre-prints

15. Ishizawa, S.; Fujimura, K.; Oisaki, K.; Sato, S.; Ohata, J.* “Catalysis in Protein Bioconjugation” ChemRxiv 2024, DOI: 10.26434/chemrxiv-2024-jxph9 [Preprint]

14. Ishizawa, S.; Uzoewulu, C. P.; Iwakura, Y.; Koirala, A.; Sato, S.; Ohata, J.* “Catalytic Serine Labeling in Nonaqueous, Acidic Media” ChemRxiv 2024, DOI: 10.26434/chemrxiv-2024-hn2m6 [Preprint]

13. Ohata, J.*; Martin, J. D.; Ison, A. “Contextual Analysis of Scientific Publications for Advancing writing Skills (CASPArS): Self-Learning for Science Writing Using Top Scientists’ Literature”  J. Chem. Edu. 2024, https://pubs.acs.org/doi/10.1021/acs.jchemed.4c00781 [Link] [Preprint]

12. Nuruzzaman. M.†; Colella, B. M.†; Nizam, Z. M.; Cho, I. J.; Zagorski, J.; Ohata, J.* “Redox-neutral, metal-free tryptophan labeling of polypeptides in hexafluoroisopropanol (HFIP)” RSC Chem. Biol. 2024, 5, 963. [Link] [2024 Emerging Investigators]

11. Nuruzzaman, M.†; Nizam, Z. M.†; Ohata, J.* “Fluoroalcohols for chemical modification of biomolecules” Tetrahedron Chem, 2024, 11, 100088. [Link] [Special issue]

10. Ohata, J.* “Friedel-Crafts Reactions for Biomolecular Chemistry” Org. Biomol. Chem., 2024, 22, 3544. [Link] [Preprint]

9. Nuruzzaman, M.; Colella, B. M.; Uzoewulu, C. P.; Meo, A. E.; Gross, E. J.; Ishizawa, S.; Sana, S.; Zhang, H.; Hoff, M. E.; Medlock, B. T. W.; Joyner, E. C.; Sato, S.; Ison, E. A.; Li, Z.; Ohata, J.* “Hexafluoroisopropanol as a Bioconjugation Medium of Ultrafast, Tryptophan-Selective Catalysis” J.  Am. Chem. Soc. 2024, 146, 10. [Link]

8. Colella, B. M.; Ohata, J.* “Small-Molecule CO2 Donors Accelerate Three-Component Peptide/Protein Bioconjugation with Alkylazides and Phosphines in Ionic Liquids” Synlett. 2024, 35, A-E. [Link] [Special issue]

7. Nizam, Z. M.; Stowe, A. M.; Mckinney, J. K.; Ohata, J.* “Iron-Sensitive Protein Conjugates Formed with a Wittig Reaction Precursor in Ionic Liquid” Chem Commun. 2023, 59, 12160. [Link]

6. Uzoewulu, C. P.; Ohata, J.* “Translation of a phosphine- and azide-based reaction to chemical modification of biomolecules in ionic liquid” Synlett. 2022, 33, 1879. [Link] [Preprint]

5. Hall, Y. D.†; Uzoewulu, C. P.†; Nizam, Z. M.; Ishizawa, S; El-Shaffey, H. M.; Ohata, J.* “Phosphine-mediated three-component bioconjugation of amino and azidosaccharides in ionic liquids” Chem Commun. 2022, 58, 10568. [Link] [Preprint] [2022 Emerging Investigators]

4. Ishizawa, S; Tumurkhuu, T; Gross, E. J.; Ohata, J.* “Correction: Site-Specific DNA Functionalization through the Tetrazene-Forming Reaction in Ionic Liquids” Chem. Sci. 2022, 13, 6749. [Link]

3. El-Shaffey, H. M.; Gross, E. J.; Hall, Y. D.; Ohata, J.* “Correction to ‘An Ionic Liquid Medium Enables Development of a Phosphine-Mediated Amine-Azide Bioconjugation Method” J. Am. Chem. Soc. 2022, 144, 9178. [Link]

2. Ishizawa, S; Tumurkhuu, T; Gross, E. J.; Ohata, J.* “Site-Specific DNA Functionalization through the Tetrazene-Forming Reaction in Ionic Liquids” Chem. Sci. 2022, 13, 1780. [Link] [Preprint]

Other publications

1. Hall, Y. D.; Gross, E. J.; El-Shaffey, H. M.; Ohata, J. “Methionine-Selective Protein Bioconjugation” Dojin News, 2021, 177, Review 2. [Link]

Jun Ohata publications before NC State

16. Hoshi, K.; Messina, M.S.; Ohata, J.; Chung C. Y.; Chang, C. J. “A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues” Nat Protoc. 2022, 17, 1691. [Link]

15. Ohata, J.; Teramoto, A.; Fujita, H.; Takemoto, S.; Matsuzaka, H. “Linear Hydrocarbon Chain Growth from a Molecular Diruthenium Carbide Platform” J. Am. Chem. Soc. 2021, 143, 16105. [Link]
14. Ohata, J.†; Krishnamoorthy, L.†; Gonzalez, M.; Xiao, T.; Iovan, D. A.; Toste, F. D.; Miller, E. W.; Chang, C. J. “An Activity-Based Methionine Bioconjugation Approach To Developing Proximity-Activated Imaging Reporters”ACS Cent. Sci. 2020, 6, 32. [Link] [Preprint]
13. Ohata, J.†; Bruemmer, K. J.†; Chang, C. J. “Activity-Based Sensing Methods for Monitoring the Reactive Carbon Species Carbon Monoxide and Formaldehyde in Living Systems” Acc. Chem. Res. 2019, 52, 2841. [Link]
12. Hanaya, K.; Ohata, J.; Miller, M. K.; Mangubat-Medina, A. E.; Swierczynski, M. J.; Yang, D. C.; Rosenthal, R. M.; Popp, B. V.; Ball, Z. T. “Rapid nickel(II)-promoted cysteine S-arylation with arylboronic acids” Chem. Commun. 2019, 55, 2841. [Link]
11. Ohata, J.; Martin, S. C.; Ball, Z. T. “Metal-Mediated Functionalization of Natural Peptides and Proteins: Panning for Bioconjugation Gold” Angew. Chem., Int. Ed. 2019, 58, 6176. [Link]
10. Ohata, J.; Ball, Z. T. “Rhodium at the chemistry-biology interface” Dalton Trans. 2018, 47, 14855. [Link]
9. Ohata, J.; Zeng, Y.; Segatori, L.; Ball, Z. T. “A Naturally Encoded Dipeptide Handle for Bioorthogonal  Chan-Lam Coupling” Angew. Chem., Int. Ed. 2018, 57, 4015. [Link]
8. Ohata, J.†; Miller, M. K.†; Mountain, C. M.; Vohidov, F.; Ball, Z. T. “A Three-Component Organometallic Tyrosine Bioconjugation” Angew. Chem., Int. Ed. 2018, 57, 2827. [Link]
7. Ohata, J.; Ball, Z. T. “A Hexa-rhodium Metallopeptide Catalyst for Site-Specific Functionalization of Natural Antibodies” J. Am. Chem. Soc. 2017, 139, 12617. [Link]
6. Ohata, J.; Ball, Z. T. “Ascorbate as a pro-oxidant: mild N-terminal modification with vinylboronic acids” Chem. Commun. 2017, 53, 1622. [Link]
5. Ohata, J.; Minus, M. B.; Abernathy, M. E.; Ball, Z. T. “Histidine-Directed Arylation/Alkenylation of Backbone N-H Bonds Mediated by Copper(II)” J. Am. Chem. Soc. 2016, 138, 7472. [Link]
4. Ohata, J.; Vohidov, F.; Ball, Z. T. “Convenient analysis of protein modification by chemical blotting with fluorogenic “click” reagents” Mol. BioSyst. 2015, 11, 2846. [Link]
3. Ohata, J.†; Vohidov, F.†; Aliyan, A.; Huang, K. W.; Marti, A. A.; Ball, Z. T. “Luminogenic iridium azide complexes” Chem. Commun. 2015, 51, 15192. [Link]
2. Vohidov, F.; Knudsen, S. E.; Leonard, P. G.; Ohata, J.; Wheadon, M. J.; Popp, B. V.; Ladbury, J. E.; Ball, Z. T. “Potent and selective inhibition of SH3 domains with dirhodium metalloinhibitors” Chem. Sci. 2015, 6, 4778. [Link]
1. Takemoto, S.; Ohata, J.; Umetani, K.; Yamaguchi, M.; Matsuzaka, H. “A diruthenium µ-carbido complex that shows singlet-carbene-like reactivity” J. Am. Chem. Soc. 2014, 136, 15889. [Link]